Despite a multiplicity of ministries playing a role in either harming or protecting biodiversity, conservation is often set as a sectoral issue, left under the responsibility of the environment ministry alone. This segregation needs be overcome through a better understanding of the role of biodiversity across government, and reviewing options for closer cooperation. The finance ministry’s direct engagement is a critical building block to make those arrangements workable. Actions include: (1) establishing joint leadership of BIOFIN by the finance and environment ministries; (2) strengthening the capacity of environment and finance ministries on matters related to financing instruments and biodiversity, respectively; and 3) improving existing coordination frameworks by expanding mandates to work on biodiversity finance. Countries have demonstrated that multiple public agencies can effectively lead the BIOFIN Process, for example the Ministry of Finance in Indonesia, the Gross National Happiness Commission in Bhutan and the Economic Planning Unit in Malaysia.